Karen Ritchie


Dr Karen Ritchie is a neuropsychologist and epidemiologist, who began her career with the Health Services Evaluation Unit, University of Oxford (Sir Richard Doll) and the Social Psychiatry Research Unit, MRC Australia (Professor Scott Henderson). She is currently Director of the French National Institute of Medical Research (INSERM), Research Unit E99-30 (Epidemiology of Nervous System Pathologies). The research work currently being undertaken by this group includes multidisciplinary population studies of neurological and psychiatric disorders in the elderly, molecular epidemiological studies of neurodegenerative and psychiatric disorder, clinical studies of senile dementia, depression, suicide, epilepsy, and care evaluation. The group also collaborates with the European Government and WHO in the development of population indicators for mental health surveillance. She is a member of the Board of Directors of the International Psychogeriatric Association, and member of the editorial board of International Psychogeriatrics, International Journal of Geriatric Psychiatry and Journal of Clinical and Experimental Gerontology. She is also a consultant to the Mental Health Division of the World Health Organisation and a member of the Advisory Committee on Women's Health for the European Government.

Publications:
  1. Ritchie K, Touchon J. Heterogeneity in senile dementia of the Alzheimer type: individual differences,progressive deterioration or clinical sub-types ? Journal of Clinical Epidemiology 1992; 45:1391-1398.
  2. Ritchie K, Robine JM, Letenneur L, Dartigues JF. Dementia-free life expectancy in France. American Journal of Public Health 1994; 84:232-236.
  3. Ritchie K, Kildea D. Is senile dementia "age-related" or "ageing related" ? Evidence from meta-analysis of dementia prevalence in the oldest old Lancet 1995; 346:931-934.
  4. Ritchie K, Leibovici D, Ledesert B, Touchon J. A typology of sub-clinical senescent cognitive disorder. British Journal of Psychiatry 1996; 168:470-476.
  5. Ritchie K, Polge C, de Roquefeuil G, Djakovic M, Ledesert B. Risk factors for dementia. Impact of anaesthesia on the cognitive functioning of the ederly. International Psychogeriatrics 1997; 9:309-326.
  6. Ritchie K. Establishing the limits of normal cerebral ageing and the senile dementias. British Journal of Psychiatry 1998; 172:97-101.
  7. Ritchie K, Touchon J, Ledesert B. Progressive disability in senile dementia is accelerated in the presence of depression. International Journal of Geriatric Psychiatry 1998; 13:459-461.
  8. Ritchie K, Touchon J, Ledesert B. Mixed cognitive and affective disorders in the elderly: A prospective study of related disability. Archives of Gerontology and Geriatrics 1998; Suppl. 6:443-450.
  9. Ritchie K, Dupuy AM. The current status of ApoE4 as a risk factor for Alzheimer's disease: An epidemiological perspective. International Journal of Geriatric Psychiatry 1999; 14:695-700.
  10. Ritchie K, Gilham C, Ledesert B, Touchon J, Kotzki PO. Depressive illness, depressive symptomatology and regional cerebral blood flow in elderly people with sub-clinical cognitive impairment. Age and Ageing 1999; 28:385-391.
  11. Ritchie K, Touchon J. Mild cognitive impairment: A critical appraisal of its conceptual basis and current nosological status. Lancet 2000; 355:225-228.
  12. Ritchie K, Artero S, Touchon J. Classification criteria for mild cognitive impairment: a population-based validation study. Neurology 2000; in press.
Discussion Paper:
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